CAD-SGE
This suite of tools enables the design of Synthetic Genetic Elements for broad host-range expression across diverse bacteria and yeast.
Ribosome Binding Sites
Generate synthetic 5' UTRs/Ribosome Binding Sites with constraints adapted for versatile microbial expression.
CDS Optimization
Our CDS optimization algorithm accounts for conserved structural elements, in particular at the N-terminus that facilitate high level expression across diverse microbial species. A custom 5' UTR/Ribosome Binding Site is generated concurrently.
Operon Generation (iDOG)
Generate a synthetic multi-gene operon, appended with expression signals to enable expression across diverse prokaryotic microbes + yeast.